INT307189

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.32
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Med1) nucleolus (Med1) nucleus (Med1)
DNA binding (Med1) transcription factor binding (Med1)
Anatomy Link Frequency
hepatocytes 2
liver 1
Med1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 37 50.00 Quite Low
Paracetamol 3 28.80 Quite Low
agonist 19 16.16 Low Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 14 82.56 Quite High
Embryonic Lethality 7 66.64 Quite High
Liver Cancer 32 54.64 Quite High
INFLAMMATION 49 50.00 Quite Low
Cancer 14 50.00 Quite Low
Hypolipidemia 2 50.00 Quite Low
Hepatotoxicity 5 27.04 Quite Low
Targeted Disruption 32 20.24 Low Low
Obesity 27 5.00 Very Low Very Low Very Low
Stress 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ligands, whereas the response of PBP/MED1-deficient hepatocytes was similar to that observed in cells that lacked PPAR?
Localization (response) of PBP in hepatocytes
1) Confidence 0.53 Published 2010 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2858266 Disease Relevance 0.12 Pain Relevance 0
ligands, whereas the response of PBP/MED1-deficient hepatocytes was similar to that observed in cells that lacked PPAR?
Localization (response) of MED1 in hepatocytes
2) Confidence 0.53 Published 2010 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2858266 Disease Relevance 0.12 Pain Relevance 0
To date, deletion of Med1 in liver has been shown to abrogate the ability of PPAR?
Localization (deletion) of Med1 in liver
3) Confidence 0.28 Published 2010 Journal PPAR Research Section Body Doc Link PMC2946606 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.

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