INT307203

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Scd1) endoplasmic reticulum (Scd1) lipid metabolic process (Scd1)
Anatomy Link Frequency
liver 1
Scd1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 75 50.00 Quite Low
Inflammation 20 50.00 Quite Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 99 99.22 Very High Very High Very High
Fatty Liver 7 92.04 High High
Diabetes Mellitus 45 74.72 Quite High
INFLAMMATION 32 50.00 Quite Low
Cancer 12 50.00 Quite Low
Hypolipidemia 1 50.00 Quite Low
Body Weight 4 44.32 Quite Low
Starvation 5 39.28 Quite Low
Overweight 3 35.36 Quite Low
Toxicity 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
also influences lipogenesis by increasing the transcription of Scd-1 and other lipogenic genes by regulating the primary transcription factors SREBP-1c and liver X receptor ?
Transcription (transcription) of Scd-1 in liver
1) Confidence 0.32 Published 2010 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2858266 Disease Relevance 0 Pain Relevance 0
Compared to wild type ob/ob mice, triglyceride content as well as mRNA levels of lipogenic genes, such as fatty acid synthase (Fasn), acetyl CoA carboxylase (Acc), and stearoyl CoA desaturase 1 (Scd1), were strongly decreased in corresponding PPAR?
Transcription (levels) of Scd1 associated with obesity
2) Confidence 0.29 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.56 Pain Relevance 0
Compared to wild type ob/ob mice, triglyceride content as well as mRNA levels of lipogenic genes, such as fatty acid synthase (Fasn), acetyl CoA carboxylase (Acc), and stearoyl CoA desaturase 1 (Scd1), were strongly decreased in corresponding PPAR?
Transcription (levels) of CoA desaturase 1 associated with obesity
3) Confidence 0.26 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.55 Pain Relevance 0

General Comments

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