INT307213

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Srebf1, Fasn) cytoplasm (Srebf1, Fasn) mitochondrion (Fasn)
lyase activity (Fasn) endoplasmic reticulum (Srebf1) DNA binding (Srebf1)
Srebf1 (Mus musculus)
Fasn (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 18 50.00 Quite Low
Paracetamol 1 12.20 Low Low
agonist 9 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 13 56.80 Quite High
INFLAMMATION 24 50.00 Quite Low
Cancer 6 50.00 Quite Low
Hypolipidemia 1 50.00 Quite Low
Overweight 1 47.76 Quite Low
Starvation 5 24.88 Low Low
Targeted Disruption 16 16.28 Low Low
Hepatotoxicity 2 13.12 Low Low
Liver Cancer 16 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SREBP-1c regulates the expression of constellations of glycolytic and lipogenic genes, including stearoyl CoA desaturase (Scd-1) and fatty acid synthase (Fas) [Hebbachi et al., 2008; Horton et al., 2002; Reddy and Rao, 2006].
SREBP-1c Regulation (regulates) of Gene_expression (expression) of fatty acid synthase
1) Confidence 0.05 Published 2010 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2858266 Disease Relevance 0.06 Pain Relevance 0

General Comments

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