INT307226

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CYLD, BCL3) structural constituent of ribosome (CYLD) ribosome (CYLD)
intracellular (CYLD) protein binding, bridging (BCL3) extracellular matrix organization (BCL3)
Anatomy Link Frequency
nucleus 2
CYLD (Homo sapiens)
BCL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 56.44 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 7 95.08 Very High Very High Very High
Cholesteatoma 60 68.48 Quite High
Apoptosis 12 63.56 Quite High
INFLAMMATION 7 56.20 Quite High
Colon Cancer 1 51.68 Quite High
Hepatocellular Cancer 1 51.00 Quite High
Carcinoma 1 49.64 Quite Low
Rheumatoid Arthritis 24 24.84 Low Low
Cancer 5 5.00 Very Low Very Low Very Low
Skin Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After translocation of Bcl-3 from the cytoplasm to the perinuclear region, CYLD removes K63-linked polyubiquitin chains from Bcl-3, and thus prevents translocation of Bcl-3 into the nucleus [10].
CYLD Negative_regulation (prevents) of Localization (translocation) of Bcl-3 in nucleus
1) Confidence 0.10 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2858283 Disease Relevance 0.45 Pain Relevance 0.06

General Comments

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