INT307307

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (COMP, EREG) extracellular region (COMP, EREG) cell differentiation (EREG)
cell adhesion (COMP) proteinaceous extracellular matrix (COMP) plasma membrane (EREG)
COMP (Homo sapiens)
EREG (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 13 99.42 Very High Very High Very High
Chondrosarcoma 12 91.08 High High
Targeted Disruption 8 72.32 Quite High
Metastasis 1 66.56 Quite High
Cancer 2 53.36 Quite High
Cytomegalovirus Infection 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results suggest that reducing mutant COMP mRNA levels may dampen the ER stress and matrix formation in the rER that is potentiated by the presence of mutant COMP.
mutant COMP Positive_regulation (potentiated) of rER associated with stress
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2858657 Disease Relevance 0.46 Pain Relevance 0

General Comments

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