INT307339

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Context Info
Confidence 0.75
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.54
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.


Pain Term Frequency Confidence Heat
ketamine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Repression 12 100.00 Very High Very High Very High
Sprains And Strains 26 88.40 High High
Stress 8 86.40 High High
Bacterial Respiratory Disease 8 34.32 Quite Low
Nosocomial And Community Acquired Bacterial Infections 2 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Bacterial Infection 4 5.00 Very Low Very Low Very Low
Hypothermia 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Staphylococcus Infection 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This result is consistent with a riboswitch-mediated guaA gene expression inhibition leading to GMP cellular depletion and RNA synthesis inhibition.
Gene_expression (expression) of guaA gene
1) Confidence 0.75 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858708 Disease Relevance 0.16 Pain Relevance 0
As predicted, bacterial growth inhibition was relieved when GMP was provided to cells grown in presence of PC1 for 2 h or 4 h, supporting the hypothesis that bacterial growth inhibition is caused by the riboswitch-mediated guaA gene repression that results in GMP cellular depletion.
Gene_expression (repression) of guaA gene associated with repression
2) Confidence 0.65 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858708 Disease Relevance 0.39 Pain Relevance 0

General Comments

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