INT307389

Context Info Confidence 0.12 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.74 Pain Relevance 0

transport (Cybb) mitochondrion (Cybb) oxidoreductase activity (Cybb) Golgi apparatus (Cybb) endoplasmic reticulum (Cybb) plasma membrane (Cybb)

Cybb (Mus musculus)

Pain Link Frequency Relevance Heat addiction 2 5.00 cytokine 2 5.00 lidocaine 1 5.00 withdrawal 1 5.00 Inflammation 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 129 94.72 Mycobacterial Infection 141 91.32 Sprains And Strains 5 70.48 Infection 66 5.00 Death 11 5.00 Neutrophil Disorders 3 5.00 Targeted Disruption 3 5.00 Ulcers 2 5.00 Hypoxia 2 5.00 Suicidal Behaviour 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It will be interesting to know if this mechanism can be extended to other pathogens such as Leishmania donovani, which is able to inhibit host cell NOX2 recruitment to the phagosome.

Negative_regulation (inhibit) of NOX2 Binding (recruitment) of

1) Confidence 0.12 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858756 Disease Relevance 0.74 Pain Relevance 0

General Comments

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