INT307407

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.67 Pain Relevance 0

cell differentiation (GLI2) cell proliferation (GLI2) nucleus (GLI2) intracellular (GLI2) cilium (GLI2) cytoplasm (GLI2)

Anatomy Link Frequency THP-1 2 GLI2 (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 2 5.00 cytokine 2 5.00 lidocaine 1 5.00 withdrawal 1 5.00 Inflammation 1 5.00

Disease Link Frequency Relevance Heat Mycobacterial Infection 141 98.60 Infection 66 91.96 Apoptosis 129 18.56 Death 11 8.92 Sprains And Strains 5 5.00 Neutrophil Disorders 3 5.00 Targeted Disruption 3 5.00 Ulcers 2 5.00 Hypoxia 2 5.00 Suicidal Behaviour 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

secretion in human THP-1 cells was inhibited by glutathione and DPI but was not affected in murine BMDMs derived from NOX2-deficient mice (Figures 3B and 3D).

Neg (not) Regulation (affected) of Localization (secretion) of THP-1 in THP-1

1) Confidence 0.01 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858756 Disease Relevance 0.67 Pain Relevance 0

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