INT307417

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cybb) mitochondrion (Cybb) oxidoreductase activity (Cybb)
Golgi apparatus (Cybb) endoplasmic reticulum (Cybb) plasma membrane (Cybb)
Anatomy Link Frequency
macrophages 2
Cybb (Mus musculus)
Cxam (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 282 97.92 Very High Very High Very High
Apoptosis 258 97.34 Very High Very High Very High
Infection 132 77.92 Quite High
Sprains And Strains 10 31.36 Quite Low
Death 22 5.00 Very Low Very Low Very Low
Neutrophil Disorders 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Ulcers 4 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Suicidal Behaviour 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, the investigation of the pro-apoptotic phenotype of a mutant of Mtb deficient in functional NDH-1 complex serendipitously revealed a novel important function of host cell NOX2 complex in macrophages.
NOX2 Binding (complex) of macrophages in macrophages associated with mycobacterial infection and apoptosis
1) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858756 Disease Relevance 0.61 Pain Relevance 0
In conclusion, the investigation of the pro-apoptotic phenotype of a mutant of Mtb deficient in functional NDH-1 complex serendipitously revealed a novel important function of host cell NOX2 complex in macrophages.
NOX2 Binding (complex) of macrophages in macrophages associated with mycobacterial infection and apoptosis
2) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858756 Disease Relevance 0.61 Pain Relevance 0

General Comments

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