INT30743

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Context Info
Confidence 0.02
First Reported 1986
Last Reported 1986
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Acot1) mitochondrion (Acot1) extracellular space (Cck)
extracellular region (Cck) lipid metabolic process (Acot1) cytoplasm (Acot1)
Anatomy Link Frequency
caudate nucleus 2
Cck (Rattus norvegicus)
Acot1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 14 100.00 Very High Very High Very High
Cholecystokinin 4 100.00 Very High Very High Very High
agonist 2 100.00 Very High Very High Very High
Dopamine 2 100.00 Very High Very High Very High
cerebral cortex 12 99.76 Very High Very High Very High
Enkephalin 2 96.08 Very High Very High Very High
substance P 2 89.92 High High
dopamine receptor 4 83.36 Quite High
antagonist 2 81.92 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of somatostatin (SOM) and cholecystokinin octapeptide (CCK-8) on basal and potassium-induced release of acetylcholine (ACh) were investigated in slices of rat caudate nucleus (CN) and, for comparison, cerebral cortex (CX).
cholecystokinin octapeptide Spec (investigated) Regulation (effects) of Localization (release) of ACh in caudate nucleus associated with somatostatin, cerebral cortex and cholecystokinin
1) Confidence 0.02 Published 1986 Journal Brain Res. Section Abstract Doc Link 2872939 Disease Relevance 0 Pain Relevance 0.66
SOM (1 microM), CCK-8 (1 microM) and the dopamine (DA) receptor agonist, apomorphine (APO, 30 microM) inhibited the K+-induced (35 mM) release of [3H]ACh by 26-32% from CN, but did not affect ACh release from CX.
CCK-8 Neg (not) Regulation (affect) of Localization (release) of ACh associated with dopamine, agonist, somatostatin and cerebral cortex
2) Confidence 0.02 Published 1986 Journal Brain Res. Section Abstract Doc Link 2872939 Disease Relevance 0 Pain Relevance 0.98

General Comments

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