INT307465

Context Info Confidence 0.10 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.07

cytosol (Gsk3a) signal transduction (Gsk3a) carbohydrate metabolic process (Gsk3a)

Gsk3a (Rattus norvegicus)

Pain Link Frequency Relevance Heat agonist 7 76.16 Glutamate 5 71.24 antagonist 4 5.00 nMDA receptor 3 5.00 withdrawal 2 5.00 addiction 2 5.00 Spinal cord 1 5.00 Inflammation 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Death 6 73.04 Apoptosis 13 63.36 Pain 1 5.00 Neurodegenerative Disease 1 5.00 INFLAMMATION 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

P2Y13 receptors were coupled to the well characterized PI3K/Akt dependent pathway, described for growth factors of the insulin family [10], resulting in the stabilization of the GSK3 substrate ?

Positive_regulation (resulting) of Positive_regulation (stabilization) of GSK3

1) Confidence 0.10 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2858808 Disease Relevance 0.24 Pain Relevance 0.07

General Comments

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