INT307630

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.41
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (BMP1) peptidase activity (BMP1) extracellular space (BMP1)
small molecule metabolic process (BMP1) extracellular region (BMP1) lipid metabolic process (BMP1)
Anatomy Link Frequency
adipose tissue 2
urine 2
BMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dextromethorphan 2 90.64 High High
withdrawal 2 75.04 Quite High
cocaine 4 72.28 Quite High
alcohol 4 70.76 Quite High
Onset of action 2 54.88 Quite High
Central nervous system 6 37.20 Quite Low
anesthesia 10 31.60 Quite Low
analgesia 6 30.40 Quite Low
depression 18 28.12 Quite Low
Hippocampus 2 22.56 Low Low
Disease Link Frequency Relevance Heat
Obesity 2 98.60 Very High Very High Very High
Poisoning 42 96.84 Very High Very High Very High
Overdose 4 71.84 Quite High
Neuroleptic Malignant Syndrome 2 69.68 Quite High
Thyroid Crisis 2 68.24 Quite High
Viral Meningitis 2 67.64 Quite High
Meningitis 2 66.96 Quite High
Sepsis 2 66.48 Quite High
Hyponatremia 2 66.16 Quite High
Hypoglycemia 4 65.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In animal experiments PCP-binding antibodies actually increased serum concentrations of PCP, indicating that they simply alter its distribution.16 PCP levels are highest in adipose tissue, and because of its slow, uneven release from lipid stores, the half-life of PCP is believed to be three days.3, 13 Due to the brain’s high lipid content and ion trapping, cerebral levels of PCP may be nine times serum levels, allowing its CNS effects to last from seven hours to as long as seven days in chronic users.17
Negative_regulation (believed) of Localization (life) of PCP in adipose tissue associated with obesity
1) Confidence 0.32 Published 2007 Journal The California Journal of Emergency Medicine Section Body Doc Link PMC2859735 Disease Relevance 0.25 Pain Relevance 0.09
The simplest way to confirm suspected PCP intoxication is via qualitative chromatographic or immunologic urine drug screen, since 9% of the active drug is excreted directly by the kidneys.11 The urine is usually positive for 2–4 days after PCP use, but after chronic exposure the test results can be positive for over a week.34
Negative_regulation (positive) of Localization (use) of PCP in urine associated with poisoning
2) Confidence 0.32 Published 2007 Journal The California Journal of Emergency Medicine Section Body Doc Link PMC2859735 Disease Relevance 1.16 Pain Relevance 0.12

General Comments

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