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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apoa1) transport (Apoa1) extracellular space (Apoa1)
extracellular region (Apoa1) nucleus (Apoa1) enzyme binding (Apoa1)
Anatomy Link Frequency
astrocytes 2
Apoa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 7 79.36 Quite High
Multiple sclerosis 48 74.48 Quite High
rheumatoid arthritis 17 70.84 Quite High
Inflammation 9 66.96 Quite High
Sciatic nerve 1 60.80 Quite High
cytokine 8 58.36 Quite High
Inflammatory response 1 24.96 Low Low
Demyelination 2 8.64 Low Low
Neuritis 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 2 97.20 Very High Very High Very High
Disorder Of Lipid Metabolism 9 93.08 High High
Demyelinating Disease 59 92.64 High High
Systemic Lupus Erythematosus 19 71.16 Quite High
Rheumatoid Arthritis 17 70.84 Quite High
INFLAMMATION 10 66.96 Quite High
Autoimmune Disease 8 64.76 Quite High
Increased Venous Pressure Under Development 1 44.24 Quite Low
Syndrome 14 23.32 Low Low
Experimental Autoimmune Encephalomyelitis 2 15.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In recent years, some researchers conformed that astrocytes generated apoA-I and apoE in rat, apoA-I facilitated translocation of newly synthesized cholesterol and phospholipid to cytosol to form the lipid-protein complex particles as an initial event in cholesterol trafficking for the assembly of HDL, and found cholesterol efflux from rat astrocytes induced by apoA-I and apoE.
Positive_regulation (generated) of Localization (translocation) of apoA-I in astrocytes associated with disorder of lipid metabolism
1) Confidence 0.49 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2860353 Disease Relevance 0.88 Pain Relevance 0.31

General Comments

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