INT307781

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Context Info
Confidence 0.76
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Apoa1, LCAT) extracellular region (Apoa1, LCAT) transport (Apoa1)
small molecule metabolic process (LCAT) transferase activity, transferring acyl groups (LCAT) enzyme binding (Apoa1)
Anatomy Link Frequency
brain 1
Apoa1 (Rattus norvegicus)
LCAT (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 7 100.00 Very High Very High Very High
Sciatic nerve 1 93.12 High High
Multiple sclerosis 48 79.28 Quite High
rheumatoid arthritis 17 61.36 Quite High
Inflammatory response 1 57.28 Quite High
Inflammation 9 53.80 Quite High
cytokine 8 45.20 Quite Low
Demyelination 2 40.96 Quite Low
Neuritis 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 9 96.52 Very High Very High Very High
Injury 2 90.24 High High
Demyelinating Disease 59 79.48 Quite High
Autoimmune Disease 8 67.84 Quite High
Rheumatoid Arthritis 17 61.36 Quite High
Systemic Lupus Erythematosus 19 60.80 Quite High
INFLAMMATION 10 57.28 Quite High
Disease 10 43.52 Quite Low
Increased Venous Pressure Under Development 1 31.08 Quite Low
Syndrome 14 10.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In CNS, apoA-I could modulate transport of cholesterol and reduce CNS impairments by activating the brain lecithin cholesterol acyl transferase (LCAT) [34-36].
apoA-I Positive_regulation (activating) of LCAT in brain associated with central nervous system
1) Confidence 0.76 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2860353 Disease Relevance 1.19 Pain Relevance 0.45

General Comments

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