INT307985

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ACOT1) lipid metabolic process (ACOT1) cytoplasm (ACOT1)
ACOT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 9 50.00 Quite Low
Neurotransmitter 5 49.08 Quite Low
Migraine 23 5.00 Very Low Very Low Very Low
Action potential 6 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
GABAergic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 15 97.44 Very High Very High Very High
Hypersensitivity 30 72.00 Quite High
Helminth Infection 22 30.64 Quite Low
Paralysis 12 9.76 Low Low
Migraine Disorders 17 5.00 Very Low Very Low Very Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Migraine With Aura 6 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transgenic expression of WT ser-4 gene rescued 5-HT sensitivity of the ser-4(ok512) mutant (Figure 9a), indicating that SER-4 function is required for exogenous 5-HT to downregulate ACh neurotransmission.
Positive_regulation (required) of Negative_regulation (downregulate) of ACh associated with targeted disruption
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2860991 Disease Relevance 0.26 Pain Relevance 0

General Comments

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