INT308128

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Context Info
Confidence 0.52
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 0.88
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (F10) extracellular region (F10) plasma membrane (F10)
Anatomy Link Frequency
platelet 2
F10 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 15 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis 125 98.72 Very High Very High Very High
Adhesions 10 80.28 Quite High
Body Weight 10 5.00 Very Low Very Low Very Low
Thrombosis Related Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In parallel with our in vitro studies, a punctate distribution of FXa was observed, in accord with the notion that FXa binding is localized to the platelet surface during thrombus formation.
Localization (localized) of FXa in platelet associated with thrombosis
1) Confidence 0.52 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2861630 Disease Relevance 0.39 Pain Relevance 0
We sought to determine where activated factor X (FXa), (pro)thrombin, and fibrin(ogen) are localized in thrombi formed under venous shear.


Localization (localized) of factor X
2) Confidence 0.52 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2861630 Disease Relevance 0.06 Pain Relevance 0
We sought to determine where activated factor X (FXa), (pro)thrombin, and fibrin(ogen) are localized in thrombi formed under venous shear.


Localization (localized) of FXa
3) Confidence 0.52 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2861630 Disease Relevance 0.06 Pain Relevance 0
Collectively, these results reveal the distinct distribution of FXa, prothrombin, and thrombin on thrombi formed under shear, and confirm the important role of exposed PS for fibrin formation under flow.


Localization (distribution) of FXa
4) Confidence 0.52 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2861630 Disease Relevance 0.25 Pain Relevance 0
Fluorescence microscopy was used to study the accumulation of platelets, FXa, (pro)thrombin, and fibrin(ogen) in thrombi formed in vitro and in vivo.
Localization (accumulation) of FXa in platelets
5) Confidence 0.45 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2861630 Disease Relevance 0.13 Pain Relevance 0

General Comments

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