INT308199

Context Info Confidence 0.45 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 4 Disease Relevance 0 Pain Relevance 0

cytoskeleton (HAP1)

HAP1 (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 8 5.00 Rsd 8 5.00

Disease Link Frequency Relevance Heat Reflex Sympathetic Dystrophy 8 5.00 Loss Of Sense Of Smell 4 5.00 Sweat Gland Disease 4 5.00 Viral Infection 4 5.00 Rheumatoid Arthritis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In Hap3, following the calculation of MAFs, the analysis procedure (detection of relatives, recalculation of Qmean, etc.) was conducted separately for the subset of Hap3 samples also present in Hap2, for all Hap3 samples, and for samples present in Hap3 only.

Positive_regulation (conducted) of Gene_expression (present) of Hap2

1) Confidence 0.45 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2861700 Disease Relevance 0 Pain Relevance 0

This allowed us to assess differences between Hap2 and Hap3 data using Hap2?

Positive_regulation (between) of Gene_expression (data) of Hap2

2) Confidence 0.45 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2861700 Disease Relevance 0 Pain Relevance 0

A test of the entire Hap3 cohort (thus including most Hap2 samples) also yielded an insignificant result (Z?

Positive_regulation (most) of Gene_expression (samples) of Hap2

3) Confidence 0.45 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2861700 Disease Relevance 0 Pain Relevance 0

This allowed us to assess differences between Hap2 and Hap3 data using Hap2?

Positive_regulation (between) of Gene_expression (using) of Hap2

4) Confidence 0.39 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2861700 Disease Relevance 0 Pain Relevance 0

General Comments

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