INT308436

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Context Info
Confidence 0.64
First Reported 2010
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.27
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Avp) extracellular space (Avp) extracellular region (Avp)
signal transducer activity (Avp)
Avp (Mus musculus)
Pain Link Frequency Relevance Heat
Dismenorea 4 81.92 Quite High
antagonist 10 37.68 Quite Low
agonist 4 20.48 Low Low
depression 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-term Labor 54 97.84 Very High Very High Very High
Death 7 93.28 High High
Dysmenorrhea 4 81.92 Quite High
Increased Venous Pressure Under Development 6 80.32 Quite High
Hypertension 54 78.88 Quite High
Acidosis 2 73.44 Quite High
Pre-eclampsia 92 63.40 Quite High
Hypoxia 4 46.56 Quite Low
Infection 5 17.68 Low Low
Premature Birth 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No PO activity was detected upon injection of Bi-proVSP, indicating that Bi-proVSP was not cleaved into the active Bi-VSP in B. mori larvae.
Neg (not) Protein_catabolism (cleaved) of VSP
1) Confidence 0.64 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2862700 Disease Relevance 0.18 Pain Relevance 0
Until now three proteases have been identified concerning the degradation of OT/AVP.
Protein_catabolism (degradation) of AVP
2) Confidence 0.55 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.16 Pain Relevance 0.08
During normal pregnancy, sufficient levels of P-LAP degrade OT and AVP, and APA deactivates AngII, thus protecting the mother.
Protein_catabolism (degrade) of AVP
3) Confidence 0.37 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.93 Pain Relevance 0.07

General Comments

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