INT308484

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Car2, Pla2g4a) cytoplasm (Car2, Pla2g4a) extracellular space (Car2)
lyase activity (Car2) Golgi apparatus (Pla2g4a) endoplasmic reticulum (Pla2g4a)
Anatomy Link Frequency
peripheral nerve 1
Car2 (Mus musculus)
Pla2g4a (Mus musculus)
Pain Link Frequency Relevance Heat
Peripheral nerve injury 13 99.96 Very High Very High Very High
dorsal root ganglion 94 85.96 High High
Brush evoked pain 48 82.72 Quite High
Calcium channel 1 78.96 Quite High
Demyelination 1 75.48 Quite High
antagonist 9 63.00 Quite High
cytokine 17 50.00 Quite Low
allodynia 5 50.00 Quite Low
Spinal nerve ligature 1 32.60 Quite Low
tetrodotoxin 1 25.16 Quite Low
Disease Link Frequency Relevance Heat
Nervous System Injury 58 99.96 Very High Very High Very High
Nociception 4 93.64 High High
Ganglion Cysts 95 85.96 High High
Neuropathic Pain 66 82.72 Quite High
Demyelinating Disease 2 75.48 Quite High
Targeted Disruption 1 52.76 Quite High
Pain 8 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After peripheral nerve injury, cPLA2 is activated by Ca2+ signaling evoked by P2X3 or P2X2/3 receptors (subtype of ionotropic purinergic receptors) [5].
Ca2 Positive_regulation (activated) of cPLA2 in peripheral nerve associated with nervous system injury and peripheral nerve injury
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2862737 Disease Relevance 1.23 Pain Relevance 0.65

General Comments

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