INT308526

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.18
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (TJP1) plasma membrane (TJP1) nucleus (TJP1)
cytoplasm (TJP1)
TJP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 5 74.20 Quite High
Inflammation 9 73.80 Quite High
alcohol 2 57.20 Quite High
Morphine 1 44.72 Quite Low
cocaine 2 14.72 Low Low
tolerance 1 7.28 Low Low
Central nervous system 21 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
Cannabinoid 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 110 98.10 Very High Very High Very High
Adhesions 11 93.52 High High
Viral Meningitis 18 85.88 High High
INFLAMMATION 8 73.80 Quite High
Infection 34 49.84 Quite Low
Drug Induced Neurotoxicity 2 31.92 Quite Low
Stress 2 8.80 Low Low
Dementia 17 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Immunodeficiency 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, HIV-1 gp120 seems capable of inducing the disruption of tight junctions by triggering proteasomal degradation of ZO-1 and ZO-2 in HBMEC [125].
Protein_catabolism (degradation) of ZO-1 associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.07 Published 2010 Journal Retrovirology Section Body Doc Link PMC2864195 Disease Relevance 1.18 Pain Relevance 0.17

General Comments

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