INT308542

Context Info Confidence 0.12 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

cytosol (AIM2) mitochondrion (AIM2) nucleolus (AIM2) nucleus (AIM2) molecular_function (AIM1) cellular_component (AIM1)

AIM1 (Homo sapiens) AIM2 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic low back pain 5 50.00 backache 53 5.00 Pain 18 5.00 complementary and alternative medicine 8 5.00 depression 3 5.00 Sciatica 3 5.00 spinal stenosis 2 5.00 Inflammation 1 5.00 Multiple sclerosis 1 5.00 Arthritis 1 5.00

Disease Link Frequency Relevance Heat Low Back Pain 61 50.00 Pain 16 5.00 Stress 15 5.00 Cognitive Disorder 6 5.00 Disease 6 5.00 Anxiety Disorder 5 5.00 Depression 3 5.00 Mental Disorders 3 5.00 Nerve Root Compression 3 5.00 Obesity 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Since assessment of Aim 3, the mediator analysis, is dependent on the results from Aim 1 and Aim 2, the study was not directly powered for Aim 3.

Aim 1 Binding (assessment) of Aim 3

1) Confidence 0.12 Published 2010 Journal Trials Section Body Doc Link PMC2864260 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.