INT308562

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.11
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (HP)
Anatomy Link Frequency
endothelial cell 2
stage 1 2
HP (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 3 63.12 Quite High
alcohol 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 136 100.00 Very High Very High Very High
Prehypertension 11 97.60 Very High Very High Very High
Obesity 1 78.72 Quite High
Cancer 28 73.84 Quite High
Renal Cancer 3 69.60 Quite High
Gastrointestinal Stromal Tumor 1 65.44 Quite High
Hemorrhage 1 63.12 Quite High
Thrombosis 1 62.16 Quite High
Nephrotoxicity 1 61.20 Quite High
Glioblastoma 1 55.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As there was no effect of treatment order on BP decrease of either intervention, subjects were classified as having prehypertension or stage 1 hypertension based on placebo values for further analysis of the treatment effects.
Neg (no) Regulation (effect) of Localization (decrease) of BP in stage 1 associated with prehypertension and hypertension
1) Confidence 0.07 Published 2010 Journal Nutr J Section Body Doc Link PMC2989300 Disease Relevance 1.33 Pain Relevance 0
Some evidence suggests that two effects of VSP inhibition on the systemic vasculature contribute to BP elevation: 1) increased vascular tone because of decreased nitric oxide production and 2) increased peripheral resistance because of endothelial cell damage and dysfunction (24–27).
Regulation (contribute) of Localization (elevation) of BP in endothelial cell
2) Confidence 0.05 Published 2010 Journal JNCI Journal of the National Cancer Institute Section Body Doc Link PMC2864290 Disease Relevance 0.78 Pain Relevance 0.03

General Comments

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