INT308647

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Bace1) peptidase activity (Bace1) extracellular space (Ager)
Golgi apparatus (Bace1) endoplasmic reticulum (Bace1) plasma membrane (Ager)
Anatomy Link Frequency
T-cells 2
Ager (Mus musculus)
Bace1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 13 97.96 Very High Very High Very High
Inflammation 18 97.56 Very High Very High Very High
Hippocampus 10 50.64 Quite High
Inflammatory response 2 27.60 Quite Low
Bile 2 24.16 Low Low
Kinase C 18 5.00 Very Low Very Low Very Low
Central nervous system 14 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
diabetic neuropathy 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 97.56 Very High Very High Very High
Disease 100 88.64 High High
Aging 8 85.08 High High
Neuroblastoma 1 83.76 Quite High
Apoptosis 6 82.76 Quite High
Death 7 71.12 Quite High
Amyloid Plaque 8 69.16 Quite High
Stress 8 59.56 Quite High
Myeloid Leukemia 4 56.32 Quite High
Diabetes Mellitus 50 55.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has also been shown that RAGE stimulates functional BACE1 expression through nuclear factor of activated T-cells 1 (NFAT1) activation, resulting in more A?
RAGE Positive_regulation (stimulates) of Gene_expression (expression) of BACE1 in T-cells
1) Confidence 0.09 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 1.01 Pain Relevance 0.12

General Comments

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