INT308660

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ager, App) cytoplasm (Ager, App) extracellular space (Ager)
cell adhesion (App) Golgi apparatus (App) extracellular matrix organization (App)
Anatomy Link Frequency
neurons 1
Ager (Mus musculus)
App (Mus musculus)
Pain Link Frequency Relevance Heat
inflammatory 18 90.08 High High
cytokine 13 89.04 High High
Hippocampus 10 61.08 Quite High
inflammatory response 2 38.04 Quite Low
kinase C 18 5.00 Very Low Very Low Very Low
central nervous system 14 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
diabetic neuropathy 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 100 99.08 Very High Very High Very High
Aging 8 95.52 Very High Very High Very High
Neuroblastoma 1 94.20 High High
Apoptosis 6 93.20 High High
INFLAMMATION 20 90.08 High High
Amyloid Plaque 8 79.60 Quite High
Stress 8 70.00 Quite High
Myeloid Leukemia 4 66.76 Quite High
Diabetes Mellitus 50 65.44 Quite High
Death 7 51.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AGE products bind to RAGE, which is present in neurons and binds to amyloidogenic APP derivative A?
RAGE Binding (binds) of APP in neurons
1) Confidence 0.08 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 1.22 Pain Relevance 0.12

General Comments

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