INT308661

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Akt1, Chuk) cytosol (Akt1, Chuk) nucleus (Akt1, Chuk)
kinase activity (Akt1, Chuk) transport (Akt1) aging (Akt1)
Akt1 (Mus musculus)
Chuk (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 18 95.84 Very High Very High Very High
cytokine 13 82.88 Quite High
Kinase C 18 81.00 Quite High
Bioavailability 2 41.08 Quite Low
Central nervous system 14 5.00 Very Low Very Low Very Low
Hippocampus 10 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
diabetic neuropathy 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 95.84 Very High Very High Very High
Increased Venous Pressure Under Development 20 91.60 High High
Diabetes Mellitus 50 90.80 High High
Chronic Disease 1 90.04 High High
Dementia 15 50.00 Quite Low
Atherosclerosis 2 42.28 Quite Low
Insulin Resistance 7 36.56 Quite Low
Congenital Anomalies 6 28.48 Quite Low
Adhesions 6 20.40 Low Low
Thrombosis 2 17.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B is phosphorylated by the upstream serine kinase IKK, which is phosphorylated and activated by additional upstream serine kinases.
kinases Positive_regulation (activated) of IKK
1) Confidence 0.02 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 0.60 Pain Relevance 0.25

General Comments

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