INT308704

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 2.09 Pain Relevance 0.10

nucleolus (DDX41) RNA binding (DDX41) nucleus (DDX41) helicase activity (DDX41)

Anatomy Link Frequency M-1 1 DDX41 (Homo sapiens) M1 (Homo sapiens)

Pain Link Frequency Relevance Heat Demyelination 7 74.20 Multiple sclerosis 14 59.64 Neuritis 11 34.48 Central nervous system 4 5.00 Sicca syndrome 3 5.00 headache 2 5.00 Spinal cord 1 5.00 Analgesic 1 5.00 Inflammation 1 5.00 Sciatica 1 5.00

Disease Link Frequency Relevance Heat Syndrome 14 99.92 Recurrence 6 99.00 Neuromyelitis Optica 94 98.96 Disease 14 98.20 Systemic Lupus Erythematosus 15 74.56 Demyelinating Disease 26 74.00 Neurological Disease 9 66.64 Transverse Myelitis 9 36.44 Optic Neuritis 10 34.48 Headache 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

M-1 and M-23 AQP4-IgG Abs are significantly associated with a higher number of relapses and longer disease duration.

Abs Binding (associated) of M-1 in M-1 associated with disease and recurrence

1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2864757 Disease Relevance 2.09 Pain Relevance 0.10

General Comments

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