INT308709

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (AQP4) helicase activity (DDX41) transmembrane transport (AQP4)
cytoplasm (AQP4) RNA binding (DDX41) nucleolus (DDX41)
AQP4 (Homo sapiens)
DDX41 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 11 93.00 High High
Multiple sclerosis 14 90.80 High High
Demyelination 7 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Sicca syndrome 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Sciatica 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 94 98.92 Very High Very High Very High
Disease 14 97.64 Very High Very High Very High
Optic Neuritis 10 93.00 High High
Demyelinating Disease 26 90.80 High High
Neurological Disease 9 90.24 High High
Recurrence 6 77.88 Quite High
Systemic Lupus Erythematosus 15 5.00 Very Low Very Low Very Low
Syndrome 14 5.00 Very Low Very Low Very Low
Transverse Myelitis 9 5.00 Very Low Very Low Very Low
Headache 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In comparison to AQP4-IgG, AQP4-IgM Abs are not a reliable biomarker, although they were elevated in definite and high risk NMO patients.
Positive_regulation (elevated) of AQP4-IgG Neg (not) Binding (biomarker) of Abs associated with neuromyelitis optica
1) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864757 Disease Relevance 1.19 Pain Relevance 0.14

General Comments

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