INT308731

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Context Info
Confidence 0.62
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cftr) transport (Cftr) ATPase activity (Cftr)
enzyme binding (Cftr) protein complex (Cftr) transmembrane transport (Cftr)
Cftr (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 96 14.24 Low Low
Inflammation 9 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukemia 3 45.56 Quite Low
Cystic Fibrosis 96 14.24 Low Low
Disorder Of Lipid Metabolism 36 5.00 Very Low Very Low Very Low
Congenital Anomalies 18 5.00 Very Low Very Low Very Low
Infection 18 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Steatorrhea 6 5.00 Very Low Very Low Very Low
Appetite Loss 6 5.00 Very Low Very Low Very Low
Exocrine Pancreatic Insufficiency 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
1000 anti-CFTR, acetyl-CoA carboxylase (ACC), AMP-activated protein kinase (AMPK), phosphorylated ACC or phosphorylated AMPK (Cell Signaling, Danvers, MA) or 1?
Phosphorylation (phosphorylated) of CFTR
1) Confidence 0.62 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864762 Disease Relevance 0 Pain Relevance 0
1000 anti-CFTR, acetyl-CoA carboxylase (ACC), AMP-activated protein kinase (AMPK), phosphorylated ACC or phosphorylated AMPK (Cell Signaling, Danvers, MA) or 1?
Phosphorylation (phosphorylated) of CFTR
2) Confidence 0.62 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864762 Disease Relevance 0 Pain Relevance 0
In line with the enhanced lipogenesis and the decreased phosphorylation state of ACC, CFTR knockdown resulted in a significant increase in SREBP-1c gene expression (Figure 10).


Phosphorylation (phosphorylation) of CFTR
3) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864762 Disease Relevance 0 Pain Relevance 0

General Comments

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