INT308804

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.42
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Pld1) signal transduction (TNF) extracellular space (TNF)
extracellular region (TNF) Golgi apparatus (Pld1) plasma membrane (TNF)
Pld1 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 123 99.12 Very High Very High Very High
chemokine 42 95.72 Very High Very High Very High
cytokine 78 95.32 Very High Very High Very High
Inflammatory response 42 84.12 Quite High
Arthritis 6 63.52 Quite High
Crohn's disease 3 49.48 Quite Low
spinal inflammation 3 48.68 Quite Low
rheumatoid arthritis 6 47.72 Quite Low
Inflammatory stimuli 3 27.20 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 165 99.12 Very High Very High Very High
Fever 9 97.32 Very High Very High Very High
Infection 18 86.76 High High
Disease 36 76.04 Quite High
Apoptosis 9 69.84 Quite High
Adhesions 24 65.48 Quite High
Systemic Lupus Erythematosus 3 65.08 Quite High
Graft Vs Host Disease 3 64.80 Quite High
Syndrome 3 63.60 Quite High
Arthritis 6 63.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-mediated proinflammatory responses, suggesting a potential role for PLD1 in TNF?
PLD1 Positive_regulation (role) of TNF
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864766 Disease Relevance 0.73 Pain Relevance 0.24
Taken together, these observations suggest a potential role for PLD1 in the TNF?
PLD1 Positive_regulation (role) of TNF
2) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864766 Disease Relevance 0.52 Pain Relevance 0.43
We have also shown that PLD1 is necessary for TNF?
PLD1 Positive_regulation (necessary) of TNF
3) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864766 Disease Relevance 1.17 Pain Relevance 0.32

General Comments

This test has worked.

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