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Context Info
Confidence 0.62
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Anxa5) intracellular (Anxa5) cytoplasm (Anxa5)
Anatomy Link Frequency
ganglion cell layer 1
external 1
Anxa5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 10 94.24 High High
potassium channel 1 78.24 Quite High
ischemia 1 69.24 Quite High
GABAergic 1 59.56 Quite High
gABA 1 55.88 Quite High
Kinase C 1 54.60 Quite High
Bioavailability 1 52.68 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 2 99.72 Very High Very High Very High
Ganglion Cysts 2 99.68 Very High Very High Very High
Apoptosis 6 96.92 Very High Very High Very High
Death 1 96.52 Very High Very High Very High
INFLAMMATION 10 94.24 High High
Adhesions 1 91.28 High High
Diabetes Mellitus 62 83.04 Quite High
Coronary Artery Disease 3 69.24 Quite High
Cancer 2 57.40 Quite High
Toxicity 6 51.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the retina, Anxa5 has been localized to the ganglion cell layer [52], where it may influence neuronal function through binding of the postsynaptic scaffolding plasma membrane protein PSD95 [53].
Localization (localized) of Anxa5 in ganglion cell layer associated with ganglion cysts
1) Confidence 0.62 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020973 Disease Relevance 0.70 Pain Relevance 0.13
Phosphatidylserine is normally localized to the inner surface of the plasma membrane, but when sublethal cell injury occurs it is translocated to the external layer the cell surface.3 Annexin V is widely used as a marker protein for the visualization of cell injury and apoptotic death in vitro.
Localization (translocated) of Annexin V in external associated with injury, apoptosis and death
2) Confidence 0.26 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2865018 Disease Relevance 0.57 Pain Relevance 0.10

General Comments

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