INT308843

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Rps6) structural constituent of ribosome (Rps6) ribosome (Rps6)
nucleolus (Rps6) nucleus (Rps6) cytoplasm (Rps6)
Rps6 (Mus musculus)
Pain Link Frequency Relevance Heat
Clonidine 7 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
antinociception 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Antinociceptive 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 50 90.08 High High
Toxicity 3 50.00 Quite Low
Tremor 11 35.04 Quite Low
Death 7 7.48 Low Low
Weight Loss 4 6.68 Low Low
Targeted Disruption 19 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Sleep Disorders 3 5.00 Very Low Very Low Very Low
Neurologic Gait Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike rapamycin, which has previously been identified as a possible therapeutic due to its upregulation of autophagy, rilmenidine had no effect on phosphorylation of p70 S6 kinase (Fig. 1G), S6 protein (Fig. 1H) or 4E-BP1 (Fig. 1I), all downstream substrates of mTOR kinase activity.


Neg (no) Regulation (effect) of Phosphorylation (phosphorylation) of S6 protein
1) Confidence 0.03 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2865373 Disease Relevance 0.16 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox