INT309107

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gsdmc) cytoplasm (Gsdmc)
Anatomy Link Frequency
neuronal 1
Gsdmc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 134 94.96 High High
bDMF 48 87.40 High High
antagonist 16 76.28 Quite High
Hippocampus 28 68.56 Quite High
anesthesia 8 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Pyramidal cell 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 118 94.96 High High
Injury 2 94.68 High High
Cognitive Disorder 32 94.24 High High
Apoptosis 10 26.64 Quite Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Death 12 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 12 5.00 Very Low Very Low Very Low
Stroke 12 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 6 5.00 Very Low Very Low Very Low
Brain Hemorrhage 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings raise the possibility that EDC activation of extranuclear estrogen receptors may involve a nongenomic to genomic signaling cascade via kinase-induced activation of the transcription factor, CREB.
Positive_regulation (activation) of extranuclear
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2866326 Disease Relevance 0.14 Pain Relevance 0.15
In conclusion, the current study demonstrates that activation of extranuclear ER results in induction of ERK-Akt-CREB-BDNF signaling in the hippocampal CA1 region, which significantly reduces ischemic neuronal injury and preserves cognitive function following GCI.
Positive_regulation (activation) of extranuclear in neuronal associated with cognitive disorder, ischemia and injury
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2866326 Disease Relevance 0.76 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox