INT309114

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tecr, Edc4) endoplasmic reticulum (Tecr) nucleus (Edc4)
Tecr (Rattus norvegicus)
Edc4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 8 99.24 Very High Very High Very High
ischemia 67 97.52 Very High Very High Very High
bDMF 24 5.00 Very Low Very Low Very Low
Hippocampus 14 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 59 97.52 Very High Very High Very High
Stroke 6 69.76 Quite High
Cognitive Disorder 16 59.00 Quite High
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 3 5.00 Very Low Very Low Very Low
Brain Hemorrhage 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intriguingly, the cell impermeable E2 conjugates, EDC and E2-BSA both exerted robust neuroprotection against GCI, an effect that appeared to be mediated by ER, as pretreatment with the ER antagonist, ICI182,780 completely abolished the neuroprotective effect of both EDC and E2-BSA.
neuroprotective Negative_regulation (effect) of EDC associated with antagonist and ischemia
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2866326 Disease Relevance 0.77 Pain Relevance 0.40

General Comments

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