INT309120

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Edc4, Mapk8) cytoplasm (Edc4, Mapk8) cytosol (Mapk8)
signal transduction (Mapk8) mitochondrion (Mapk8) kinase activity (Mapk8)
Edc4 (Rattus norvegicus)
Mapk8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 67 99.72 Very High Very High Very High
bDMF 24 82.88 Quite High
Hippocampus 14 45.68 Quite Low
antagonist 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 59 99.72 Very High Very High Very High
Death 6 99.08 Very High Very High Very High
Apoptosis 5 97.32 Very High Very High Very High
Targeted Disruption 9 92.32 High High
Cognitive Disorder 16 91.60 High High
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Stroke 6 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 3 5.00 Very Low Very Low Very Low
Brain Hemorrhage 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the ability of EDC to markedly attenuate JNK activation after GCI likely contributes significantly to its neuroprotective actions.
EDC Negative_regulation (attenuate) of Positive_regulation (activation) of JNK associated with ischemia
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2866326 Disease Relevance 1.03 Pain Relevance 0.36

General Comments

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