INT309124

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Dlat, Mapk8) cytosol (Mapk8) signal transduction (Mapk8)
nucleus (Mapk8) transferase activity, transferring acyl groups (Dlat) kinase activity (Mapk8)
Dlat (Rattus norvegicus)
Mapk8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 67 98.52 Very High Very High Very High
Hippocampus 14 92.12 High High
bDMF 24 48.68 Quite Low
antagonist 8 36.96 Quite Low
agonist 2 7.20 Low Low
anesthesia 4 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 59 98.52 Very High Very High Very High
Death 6 37.52 Quite Low
Apoptosis 5 36.08 Quite Low
Cv Unclassified Under Development 6 30.24 Quite Low
Middle Cerebral Artery Infarction 3 29.44 Quite Low
Cognitive Disorder 16 5.00 Very Low Very Low Very Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Stroke 6 5.00 Very Low Very Low Very Low
Brain Hemorrhage 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, we recently demonstrated that E2 attenuates the rapid activation of the proapoptotic signaling kinase, JNK in the hippocampal CA1 region after GCI [6].
E2 Negative_regulation (attenuates) of Positive_regulation (activation) of JNK associated with ischemia
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2866326 Disease Relevance 0.27 Pain Relevance 0.22

General Comments

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