INT309176

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.12
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Proc) extracellular space (Proc) extracellular region (Proc)
Anatomy Link Frequency
satellite cells 2
Proc (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 98.28 Very High Very High Very High
cytokine 22 87.56 High High
ischemia 10 86.28 High High
metalloproteinase 9 65.92 Quite High
chemokine 2 25.04 Quite Low
Inflammatory response 2 12.12 Low Low
fibrosis 6 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 103 99.70 Very High Very High Very High
Wound Healing 34 99.46 Very High Very High Very High
Injury 157 99.38 Very High Very High Very High
Reperfusion Injury 46 99.24 Very High Very High Very High
INFLAMMATION 41 98.28 Very High Very High Very High
Stress 3 92.24 High High
Cancer 48 89.36 High High
Cv Unclassified Under Development 17 86.28 High High
Metastasis 4 85.52 High High
Disease 4 79.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Impaired wound healing in diabetes is related to decreased production of growth factors.
Negative_regulation (decreased) of Gene_expression (production) of factors associated with diabetes mellitus and wound healing
1) Confidence 0.01 Published 2010 Journal Genet Vaccines Ther Section Abstract Doc Link PMC2939607 Disease Relevance 0.47 Pain Relevance 0
In animal models of impaired wound healing diminished neovascularization is also associated with delayed or diminished production of VEGF-A and other angiogenic growth factors [5].
Negative_regulation (diminished) of Gene_expression (production) of factors associated with wound healing
2) Confidence 0.01 Published 2010 Journal Genet Vaccines Ther Section Body Doc Link PMC2939607 Disease Relevance 0.66 Pain Relevance 0.12
The lower rate and extent of muscle regeneration after IR injury was not related to a specific loss of satellite cells, nor to a decreased capillary bed density or expression of major growth factors controlling myogenesis.
Neg (nor) Negative_regulation (loss) of Gene_expression (expression) of factors in satellite cells associated with reperfusion injury and injury
3) Confidence 0.01 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 1.42 Pain Relevance 0.09
B activation may reduce expression of these growth factors.
Spec (may) Negative_regulation (reduce) of Gene_expression (expression) of factors
4) Confidence 0.00 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 0.57 Pain Relevance 0.14

General Comments

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