INT30918

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Context Info
Confidence 0.45
First Reported 1986
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.72
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Hexb) lysosome (Hexb)
Anatomy Link Frequency
urine 2
Hexb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 92.68 High High
Dynorphin 4 87.68 High High
palliative 2 77.04 Quite High
Disease Link Frequency Relevance Heat
Nephrotoxicity 10 91.80 High High
Necrosis 2 77.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CP significantly increased the concentration of urea and creatinine (P < 0.05) by about 128% and 170%, respectively; increased urine volume and N-acetyl-beta-D-glucosaminidase (NAG) activity; and significantly decreased osmolality and protein concentrations.
Positive_regulation (increased) of N-acetyl-beta-D-glucosaminidase in urine
1) Confidence 0.45 Published 2008 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 18445776 Disease Relevance 0.37 Pain Relevance 0.08
CP treatment significantly increased urine volume and N-acetyl-beta-D-glucosaminidase (NAG) activity, and significantly decreased osmolality and protein concentrations.
Positive_regulation (increased) of N-acetyl-beta-D-glucosaminidase in urine
2) Confidence 0.42 Published 2007 Journal Fundam Clin Pharmacol Section Abstract Doc Link 17868208 Disease Relevance 0.35 Pain Relevance 0.07
Ovariectomy produced an increase in the levels of ir-Dyn A, Dyn B, alpha-nEnd, beta-nEnd, and LE 2 weeks after surgery, but, in contrast to castration, no significant decrease was seen 3 days after ovariectomy.
Positive_regulation (increase) of beta-nEnd
3) Confidence 0.01 Published 1986 Journal Endocrinology Section Abstract Doc Link 2876888 Disease Relevance 0 Pain Relevance 0.24

General Comments

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