INT309253

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LMOD1) cytoskeleton (LMOD1) cytoplasm (LMOD1)
Anatomy Link Frequency
striatum 2
LMOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 6 100.00 Very High Very High Very High
Dopamine 14 99.02 Very High Very High Very High
cocaine 2 81.04 Quite High
dopamine receptor 1 71.64 Quite High
antagonist 3 68.64 Quite High
Glutamate 8 46.36 Quite Low
gABA 18 45.80 Quite Low
Serotonin 3 42.40 Quite Low
agonist 5 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 5 100.00 Very High Very High Very High
Targeted Disruption 2 95.56 Very High Very High Very High
Ataxia 73 5.00 Very Low Very Low Very Low
Cerebellar Ataxia 37 5.00 Very Low Very Low Very Low
Disease 22 5.00 Very Low Very Low Very Low
Cerebellar Diseases 9 5.00 Very Low Very Low Very Low
Spinocerebellar Ataxia Type 2 9 5.00 Very Low Very Low Very Low
Syndrome 9 5.00 Very Low Very Low Very Low
Neuropathy 7 5.00 Very Low Very Low Very Low
Tremor 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Extra-cellular dopamine levels are increased in the striatum, causing a depression in mRNA levels of both D1 and D2 receptors and decreased stores of dopamine [71, 96].
Negative_regulation (depression) of Transcription (levels) of D1 in striatum associated with dopamine and depression
1) Confidence 0.03 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2866461 Disease Relevance 0.20 Pain Relevance 0.57

General Comments

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