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Context Info
Confidence 0.49
First Reported 1986
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.34
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GGT1) plasma membrane (GGT1) transferase activity, transferring acyl groups (GGT1)
cellular amino acid metabolic process (GGT1)
Anatomy Link Frequency
liver 2
GGT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 2 99.92 Very High Very High Very High
Paracetamol 15 99.52 Very High Very High Very High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Balkan Nephropathy 6 96.84 Very High Very High Very High
Renal Disease 8 96.52 Very High Very High Very High
Obesity 4 94.56 High High
Diuresis 3 92.92 High High
Nephrotoxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased excretion of LDH and GGT indicated a similar moderate damage of the tubular epithelia after phenacetin and paracetamol.
Positive_regulation (Increased) of Localization (excretion) of GGT associated with paracetamol
1) Confidence 0.49 Published 1986 Journal Clin. Chim. Acta Section Abstract Doc Link 2877759 Disease Relevance 0.17 Pain Relevance 0.43
After acetaminophen administration urinary excretion of APN, dipeptidylpeptidase IV (DPP IV), gamma-glutamyltranspeptidase (GGT) and N-acetyl-beta-D-glucosaminidase (NAGA) did not increase significantly in any group studied.
Neg (not) Positive_regulation (increase) of Localization (excretion) of GGT associated with paracetamol
2) Confidence 0.49 Published 1999 Journal Ren Fail Section Abstract Doc Link 10516997 Disease Relevance 0.98 Pain Relevance 0.81
METHODS: We prospectively evaluated the levels of the serum concentration of liver enzymes aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), gamma glutamyl transferase (GGT), alkaline phosphatase (ALP), and total bilirubin (TBil), in 42 morbidly obese and 40 non obese patients who were scheduled for elective abdominal surgery under sevoflurane anesthesia at the Jordan University Hospital, Amman, Jordan.
Positive_regulation (enzymes) of Localization (aspartate aminotransferase) of GGT in liver
3) Confidence 0.49 Published 2009 Journal Middle East J Anesthesiol Section Body Doc Link 19583067 Disease Relevance 0.19 Pain Relevance 0

General Comments

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