INT309486

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Chek1) nucleus (Chek1) cell cycle (Chek1)
kinase activity (Chek1) cytoplasm (Chek1)
Chek1 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 6 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 6 99.16 Very High Very High Very High
Repression 2 92.08 High High
Disease 50 84.64 Quite High
Aging 6 35.64 Quite Low
Cerebellar Ataxia 1 22.96 Low Low
Werner Syndrome 1 17.88 Low Low
Cockayne Syndrome 1 14.52 Low Low
Adenovirus Infection 2 13.20 Low Low
Neurodegenerative Disease 2 11.04 Low Low
Targeted Disruption 33 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nonrepaired DSB foci will attract ATM and associated molecules (Bekker-Jensen et al., 2006), activate Chk1 and 2, and initiate apoptotic signaling (for review see Sancar et al., 2004).
Positive_regulation (activate) of Chk1 associated with apoptosis
1) Confidence 0.22 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2867301 Disease Relevance 0.60 Pain Relevance 0

General Comments

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