INT309527

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.74
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (CASZ1) nucleus (CASZ1) intracellular (CASZ1)
DNA binding (CASZ1) cytoplasm (CASZ1)
Anatomy Link Frequency
spinal cord 2
lateral 1
interneurons 1
CASZ1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 100 97.88 Very High Very High Very High
interneuron 10 96.00 Very High Very High Very High
Multiple sclerosis 17 93.52 High High
imagery 33 5.00 Very Low Very Low Very Low
medulla 16 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Demyelination 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Neuritis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 51 99.78 Very High Very High Very High
Multiple Sclerosis 21 93.52 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 76 75.52 Quite High
Pathologic Processes 2 65.92 Quite High
Recurrence 8 50.00 Quite Low
Cytomegalovirus Infection 14 5.00 Very Low Very Low Very Low
Frailty 12 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 5 5.00 Very Low Very Low Very Low
Demyelinating Disease 4 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Turning to the conventional diffusion indices, patients showed a greater increase in the FA of the left lateral CST-ROI compared with controls over time (by 0.01?
Positive_regulation (increase) of CST-ROI in lateral
1) Confidence 0.43 Published 2010 Journal Multiple Sclerosis (Houndmills, Basingstoke, England) Section Body Doc Link PMC2951108 Disease Relevance 0.16 Pain Relevance 0.07
Stimulation of the CST in cats produces clear disynaptic responses in motoneurons (Illert et al. 1976); this is transmitted both via segmental interneurons and also by C3–4 propriospinal interneurons (Alstermark and Sasaki 1985; Illert et al. 1977).
Positive_regulation (Stimulation) of CST in interneurons
2) Confidence 0.07 Published 2010 Journal Journal of Neurophysiology Section Body Doc Link PMC2867561 Disease Relevance 0 Pain Relevance 0.18
These data show that delaying the overexpression of NCS1 in CSN after injury can still induce intact CST axons to sprout into the CST-denervated side of the spinal cord.


Positive_regulation (induce) of CST in spinal cord associated with injury and spinal cord
3) Confidence 0.02 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2889931 Disease Relevance 0.51 Pain Relevance 0.14
These data show that overexpression of NCS1 in CSN at the cortical level can induce intact CST to form functional connections in the CST-denervated side of the spinal cord.


Positive_regulation (induce) of CST in spinal cord associated with spinal cord
4) Confidence 0.02 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2889931 Disease Relevance 0.07 Pain Relevance 0.09

General Comments

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