INT309661

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Context Info
Confidence 0.51
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Akt1) aging (Akt1) enzyme binding (Akt1)
carbohydrate metabolic process (Akt1) cytoplasm (Akt1) cytosol (Akt1)
Anatomy Link Frequency
macrophages 2
C5 (Rattus norvegicus)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 12 87.04 High High
Arthritis 56 85.44 High High
Inflammation 15 14.76 Low Low
rheumatoid arthritis 9 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 59 85.44 High High
Pressure And Volume Under Development 16 65.04 Quite High
Disease 10 47.76 Quite Low
Hypersensitivity 9 22.00 Low Low
INFLAMMATION 15 14.76 Low Low
Rheumatoid Arthritis 9 5.00 Very Low Very Low Very Low
Immunization 3 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Autoimmune Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our experiments, C5a induced phosphorylation of Akt in wildtype macrophages in vitro, while no phosphorylation could be observed in PI3K?
C5a Positive_regulation (induced) of Phosphorylation (phosphorylation) of Akt in macrophages
1) Confidence 0.51 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2867834 Disease Relevance 0.45 Pain Relevance 0.21

General Comments

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