INT309708

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk) plasma membrane (Palm) cytoskeleton organization (Palm)
cytoplasm (Palm)
Anatomy Link Frequency
brain 2
Palm (Mus musculus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 45 100.00 Very High Very High Very High
Enkephalin 21 100.00 Very High Very High Very High
Nucleus accumbens 6 90.24 High High
Hippocampus 15 72.64 Quite High
Pain 7 37.20 Quite Low
Pain threshold 1 35.96 Quite Low
Lasting pain 1 28.60 Quite Low
Opioid 7 26.60 Quite Low
narcan 3 20.80 Low Low
tolerance 1 15.68 Low Low
Disease Link Frequency Relevance Heat
Post-traumatic Stress Disorder 55 97.92 Very High Very High Very High
Depression 20 91.12 High High
Anxiety Disorder 50 90.52 High High
Targeted Disruption 3 50.00 Quite Low
Pain 8 37.20 Quite Low
Stress 15 27.96 Quite Low
Urological Neuroanatomy 4 5.00 Very Low Very Low Very Low
Depressive Disorder 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Multiple brain areas, such as the M1, BSTL, BNST, PaLM, CeA, and BLA, appear to be involved in the activation of endogenous enkephalins during the reexperiencing of traumatic events and avoidance of traumatic stimuli that characterize PTSD.


PaLM Regulation (involved) of Positive_regulation (activation) of enkephalin in brain associated with post-traumatic stress disorder, enkephalin and amygdala
1) Confidence 0.19 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2867948 Disease Relevance 1.25 Pain Relevance 0.91

General Comments

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