INT309831

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Zfp366) molecular_function (Zfp366) biological_process (Zfp366)
Anatomy Link Frequency
internal 1
Zfp366 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 54 98.16 Very High Very High Very High
Infection 27 97.52 Very High Very High Very High
Disease 2 11.92 Low Low
Body Weight 7 5.00 Very Low Very Low Very Low
Weight Loss 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Viral Infection 3 5.00 Very Low Very Low Very Low
Dengue 1 5.00 Very Low Very Low Very Low
Lymphocytic Choriomeningitis 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we chose the C57BL/6 (B6) mouse model to assess the extent of heterosubtypic immunity based on the following considerations: (1) Both CD8 and CD4 T cell epitope repertoire of influenza A virus have been extensively characterized in B6 mice and a Db-restricted, immunodominant NP366 epitope is the major target to mediate a protective, memory CTL response after secondary infections with influenza A viruses [25]–[28]. (2) Analysis of the deduced amino acid sequences of the NP gene from a large number of influenza A viruses (955 sequences), indicated that, certain amino acid residues within the NP366/Db CTL epitope undergo constant evolutionary change (Table 1), despite the overall conserved nature of this internal protein between different influenza A virus subtypes (?
Regulation (target) of NP366 in internal associated with influenza virus infection and infection
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2868023 Disease Relevance 0.72 Pain Relevance 0

General Comments

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