INT309866

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

histone binding (Lef1) cell adhesion (Lef1) nucleus (Lef1)
DNA binding (Lef1) transcription factor binding (Lef1) cytoplasm (Lef1)
Lef1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 5 89.56 High High
gABA 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 21 90.84 High High
INFLAMMATION 5 89.56 High High
Familial Adenomatous Polyposis 6 74.56 Quite High
Cancer 14 69.36 Quite High
Intestinal Cancer 1 58.64 Quite High
Aberrant Crypt Foci 29 50.00 Quite Low
Cleidocranial Dysplasia 1 12.20 Low Low
Body Weight 5 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 3 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been demonstrated that the COX-2 5' regulatory region contains the consensus Lef-1 binding motive, thus supporting the hypothesis that COX-2 expression is mediated through Wnt (the name derived from lnt-1 and Drosophila wingless) signalling pathway.
Lef-1 Binding (binding) of
1) Confidence 0.04 Published 2010 Journal Nutr J Section Body Doc Link PMC2868780 Disease Relevance 0.64 Pain Relevance 0.09

General Comments

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