INT309906

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EGF, SRC) plasma membrane (EGF, SRC) mitochondrion (SRC)
cytoplasm (SRC) cytosol (SRC) extracellular space (EGF)
EGF (Homo sapiens)
SRC (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 16 97.72 Very High Very High Very High
Disease Progression 1 78.32 Quite High
Adhesions 1 73.96 Quite High
Chronic Myeloid Leukemia 2 65.20 Quite High
Renal Cancer 1 57.00 Quite High
Solid Tumor 5 56.88 Quite High
Gastrointestinal Stromal Tumor 1 56.00 Quite High
Head & Neck Cancer 2 50.00 Quite Low
Disease 8 45.92 Quite Low
Apoptosis 3 33.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In these experiments inhibition of Src kinases in originally cetuximab-resistant cell lines resulted in a regaining of sensitivity against cetuximab, indicating a close interaction between Src and EGF-R regarding the processes causing cetuximab resistance in tumour cells [27].
EGF-R Binding (interaction) of Src associated with cancer
1) Confidence 0.11 Published 2010 Journal Head Neck Oncol Section Body Doc Link PMC2868849 Disease Relevance 0.64 Pain Relevance 0

General Comments

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