INT309938

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.26
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Psmd4) cytoplasm (Psmd4)
Anatomy Link Frequency
eosinophil 1
Psmd4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 42 87.84 High High
chemokine 3 34.36 Quite Low
cytokine 9 33.88 Quite Low
corticosteroid 3 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diphtheria 1 100.00 Very High Very High Very High
Targeted Disruption 1 96.86 Very High Very High Very High
Hypersensitivity 7 87.92 High High
INFLAMMATION 43 87.84 High High
Rhinitis 7 87.04 High High
Asthma 74 69.68 Quite High
Occupational Lung Diseases 18 68.08 Quite High
Disease 22 48.16 Quite Low
Bronchitis 9 18.76 Low Low
Eosinophilia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a definitive role for eosinophils could not be established until Lee and colleagues developed an eosinophil-deficient transgenic line of mice, the PHIL mouse, using a method involving the developmental ablation of eosinophil peroxidase-expressing progenitor cells through simultaneous activation of the diphtheria toxin A chain protein [41].
Positive_regulation (activation) of chain protein in eosinophil associated with targeted disruption and diphtheria
1) Confidence 0.01 Published 2008 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2868889 Disease Relevance 1.26 Pain Relevance 0.19

General Comments

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