INT309941

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.31
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Edn1, Tlr2) signal transduction (Tlr2) extracellular space (Edn1)
extracellular region (Edn1) plasma membrane (Tlr2) intracellular (Tlr2)
Anatomy Link Frequency
dendritic cells 1
Edn1 (Mus musculus)
Tlr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 42 83.84 Quite High
tolerance 1 34.88 Quite Low
cytokine 9 29.44 Quite Low
chemokine 3 22.88 Low Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 7 97.28 Very High Very High Very High
Disease 22 96.56 Very High Very High Very High
Asthma 74 95.60 Very High Very High Very High
Eczema 1 91.52 High High
Rhinitis 7 90.24 High High
INFLAMMATION 43 83.84 Quite High
Apoptosis 3 72.84 Quite High
Occupational Lung Diseases 18 59.04 Quite High
Bronchitis 9 56.64 Quite High
Eosinophilia 3 31.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subsequent studies from the same authors demonstrated that intratracheal instillation of OVA-loaded dendritic cells pretreated with EDN led to the enhancement of an OVA-specific Th2 response in the mouse through direct activation of Toll-like receptor 2 by EDN [60].


EDN Positive_regulation (activation) of Toll-like receptor 2 in dendritic cells
1) Confidence 0.02 Published 2008 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2868889 Disease Relevance 1.31 Pain Relevance 0.07

General Comments

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