INT309972

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cdh2) plasma membrane (Cdh2) protein complex (Cdh2)
Cdh2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 11 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Nav1.6 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Nav1.1 1 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
nav1.3 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 2 94.72 High High
Myocardial Infarction 4 87.00 High High
Cardiomyopathy 5 86.28 High High
Dilated Cardiomyopathy 6 81.96 Quite High
Heart Rate Under Development 3 70.68 Quite High
Sprains And Strains 1 69.00 Quite High
Stress 2 61.28 Quite High
Syndrome 5 58.64 Quite High
Arrhythmogenic Right Ventricular Dysplasia 1 57.68 Quite High
Cleidocranial Dysplasia 7 53.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additional studies have shown a close interaction between the mechanical and electrical components of the intercalated disk since loss of N-cadherin disrupts connexin localization and cardiac impulse propagation [6], and correct targeting of Cx43 to the ID depends on transport of the intact protein to cadherin-containing adherens junctions of the disk [7].
Negative_regulation (loss) of N-cadherin
1) Confidence 0.13 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2868981 Disease Relevance 0.90 Pain Relevance 0

General Comments

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