INT310097

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.28
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (H1fnt) chromosome (H1fnt) nucleus (H1fnt)
DNA binding (H1fnt)
Anatomy Link Frequency
T cells 1
H1fnt (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 1 65.20 Quite High
Inflammation 1 63.76 Quite High
Paracetamol 2 62.44 Quite High
headache 9 50.64 Quite High
alcohol 1 43.84 Quite Low
imagery 1 38.44 Quite Low
cytokine 8 20.40 Low Low
drug abuse 1 17.28 Low Low
Analgesic 8 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 282 100.00 Very High Very High Very High
Thrombocytopenia 1 82.00 Quite High
Lymphopenia 1 75.76 Quite High
Fever 36 75.60 Quite High
Pressure Volume 2 Under Development 1 69.76 Quite High
Hypoxia 1 68.40 Quite High
INFLAMMATION 1 63.76 Quite High
Sprains And Strains 93 53.56 Quite High
Cough 5 52.88 Quite High
Chills 3 52.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clinical presentation of patients who tested positive for 2009 pandemic influenza A (H1N1) virus
Positive_regulation (tested) of H1N1 associated with influenza virus infection
1) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2871038 Disease Relevance 1.74 Pain Relevance 0.18
The studies included HAI testing based on guidance from the US FDA for consistency with inactivated H1N1 vaccine studies.
Positive_regulation (inactivated) of H1N1
2) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2966412 Disease Relevance 0.17 Pain Relevance 0
These studies were designed to rapidly provide the US FDA with sufficient information to guide licensure decisions regarding MedImmune's monovalent live attenuated 2009 H1N1 vaccine in the setting of a widespread H1N1 pandemic; as a result they have a number of limitations.
Positive_regulation (vaccine) of H1N1
3) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2966412 Disease Relevance 0.32 Pain Relevance 0
Using the homologous stimulant, H1N1/CA antigen, induction of about 0.25% of CD4 T cells by the live vectors was achieved.
Positive_regulation (induction) of H1N1 in T cells
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922371 Disease Relevance 0.06 Pain Relevance 0
With the Brisbane (H1N1/BR) and with the H5N1/VN antigens, good levels of cross reactivity were seen, while the New Caledonia H1N1 antigen (H1N1/NC) was a poor stimulant (Fig. 5A).
Positive_regulation (stimulant) of H1N1
5) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922371 Disease Relevance 0 Pain Relevance 0

General Comments

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